General Information:

Id: 5,627
Diseases: Cardiomyopathy, hypertrophic
Mammalia
article
Reference: Menick DR et al.(2013) Transcriptional pathways and potential therapeutic targets in the regulation of Ncx1 expression in cardiac hypertrophy and failure Adv. Exp. Med. Biol. 961: 125-135 [PMID: 23224875]

Interaction Information:

Comment reatment of neonatal or adult cardiomyocytes with TGF-beta, TNF-alpha, endothelin-1, or angiotensin II induces profound changes in cardiac gene expression including the reexpression of fetal isoforms of contractile proteins including beta-myosin heavy chain, alpha-skeletal actin, and increased production of “stress markers” such as atrial natriuretic factor (ANF) and B-type natriuretic peptide (BNP). (cited information)
Formal Description
Interaction-ID: 53806

gene/protein

TGFB1

increases_expression of

gene/protein

MYH7

Drugbank entries Show/Hide entries for TGFB1 or MYH7