General Information:

Id: 422 (click here to show other Interactions for entry)
Diseases: Amyotrophic lateral sclerosis
Homo sapiens
MO59J glioblastoma cell line, transfected with WT, L8Q and G93A forms of human SOD1
Reference: Harraz MM et al.(2008) SOD1 mutations disrupt redox-sensitive Rac regulation of NADPH oxidase in a familial ALS model J. Clin. Invest. 118: 659-670 [PMID: 18219391]

Interaction Information:

Comment Both SOD1G93A and SOD1L8Q mutant proteins elevated Rac1-GTP levels in MO59J cells compared with overexpression of SOD1WT.
Formal Description
Interaction-ID: 1842

gene/protein mutant


affects_activity of



if SOD1G93A is overexpressed
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