General Information:

Id: 417 (click here to show other Interactions for entry)
Diseases: Amyotrophic lateral sclerosis
Mus musculus
SOD1G93A transgenic mouse, transfected with human SOD1G93A
BTO:0001279 spinal cord
Reference: Harraz MM et al.(2008) SOD1 mutations disrupt redox-sensitive Rac regulation of NADPH oxidase in a familial ALS model J. Clin. Invest. 118: 659-670 [PMID: 18219391]

Interaction Information:

Comment Transgenic mice overexpressing SOD1G93A demonstrated an greater enhancement in Rac1-GTP levels (i.e., activated Rac1) compared with nontransgenic age-matched controls.
Formal Description
Interaction-ID: 1832

gene/protein mutant


affects_activity of



if SOD1G93A is overexpressed
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