General Information:

Id: 391 (click here to show other Interactions for entry)
Diseases: Amyotrophic lateral sclerosis
Mus musculus
SOD1(G93A) transgenic mouse
BTO:0001279 spinal cord; BTO:0000312 motoneuron
Reference: Kiaei M et al.(2006) Thalidomide and lenalidomide extend survival in a transgenic mouse model of amyotrophic lateral sclerosis J. Neurosci. 26: 2467-2473 [PMID: 16510725]

Interaction Information:

Comment IL-12p40 RNA was elevated in vehicle-treated G93A mice compared with wild type (N1020 controls) and significantly reduced in both lenalidomide- and thalidomide- treated G93A mice.
Formal Description
Interaction-ID: 1688

gene/protein mutant


increases_expression of



in spinal cord; at 110 days of age
Drugbank entries Show/Hide entries for IL12B