General Information:

Id: 3,655 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Mus musculus
Reference: Gutgesell A et al.(2009) Mouse carnitine-acylcarnitine translocase (CACT) is transcriptionally regulated by PPARalpha and PPARdelta in liver cells Biochim. Biophys. Acta 1790: 1206-1216 [PMID: 19577614]

Interaction Information:

Comment Mouse carnitine-acylcarnitine translocase (CACT) is upregulated by PPARalpha and PPARdelta in hepatocytes. The upregulation of CACT by PPARalpha and PPARdelta, which are both important for the regulation of fatty acid oxidation in tissues during fasting, may increase the import of acylcarnitine into the mitochondrial matrix during fasting.
Formal Description
Interaction-ID: 34745



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