General Information:

Id: 3,503 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Mus musculus
PPARalpha-/- mouse
Reference: Makowski L et al.(2009) Metabolic profiling of PPARalpha-/- mice reveals defects in carnitine and amino acid homeostasis that are partially reversed by oral carnitine supplementation FASEB J. 23: 586-604 [PMID: 18945875]

Interaction Information:

Comment In comparison to wild-type animals, free carnitine levels were dramatically reduced in plasma, muscle, and liver of PPARalpha -/- mice; this was apparent in both the fed and fasted states.
Formal Description
Interaction-ID: 32564



affects_quantity of

drug/chemical compound


in blood plasma, in liver, in skeletal muscle
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