General Information:

Id: 3,167 (click here to show other Interactions for entry)
Diseases: Alzheimer disease - [OMIM]
Homo sapiens
Reference: Grimmer T et al.(2010) Progression of cerebral amyloid load is associated with the apolipoprotein E epsilon4 genotype in Alzheimers disease Biol. Psychiatry 68: 879-884 [PMID: 20598287]

Interaction Information:

Comment A significant increase of amyloid deposition occurs in patients with AD during a relatively short interval of its clinical course. The rate of amyloid aggregation rate is closely associated with the apolipoprotein E (epsilon 4) genotype.
Formal Description
Interaction-ID: 29109

gene/protein mutant

APOE (isoform E4)

increases_quantity of