General Information:

Id: 2,533 (click here to show other Interactions for entry)
Diseases: Alzheimer disease - [OMIM]
Reference: Di Paolo G and Kim TW(2011) Linking lipids to Alzheimers disease: cholesterol and beyond. Nat. Rev. Neurosci. 12: 284-296 [PMID: 21448224]

Interaction Information:

Comment The epsilon 4 allele of the apolipoprotein E (APOE) gene was identified as the strongest genetic risk factor for AD.
Formal Description
Interaction-ID: 23594

gene/protein mutant

APOE (isoform E4)

increases_activity of