General Information:

Id: 238 (click here to show other Interactions for entry)
Diseases: Amyotrophic lateral sclerosis
Mus musculus
SOD1(G93A) transgenic mouse
BTO:0001279 spinal cord
Reference: Ying Z et al.(2009) Gp78, an ER associated E3, promotes SOD1 and ataxin-3 degradation Hum. Mol. Genet. 18: 4268-4281 [PMID: 19661182]

Interaction Information:

Comment Mutant SOD1 induces aggregate formation. In spinal cords of SOD1G93A transgenic mice, gp78 was colocalized onto the SOD1 aggregates and the ubiquitinated aggregates.
Formal Description
Interaction-ID: 13348

gene/protein mutant


increases_quantity of


SOD1 protein aggregates