General Information:

Id: 2,212 (click here to show other Interactions for entry)
Diseases: Alzheimer disease - [OMIM]
Endocrine
Homo sapiens
article
Reference: Mateos L et al.(2011) Upregulation of brain renin angiotensin system by 27-hydroxycholesterol in Alzheimers disease J. Alzheimers Dis. 24: 669-679 [PMID: 21297254]

Interaction Information:

Comment ACE activity in the CSF is positively correlated with both plasma and CSF levels of 27-hydroxycholesterol (27-OH), an oxysterol known to pass through the blood-brain barrier and taken up from the circulation by the brain.
Formal Description
Interaction-ID: 18600

drug/chemical compound

27-Hydroxycholesterol

affects_activity of

gene/protein

ACE

in plasma and the cerebrospinal fluid (CSF)
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