General Information:

Id: 2,098 (click here to show other Interactions for entry)
Diseases: Alzheimer disease - [OMIM]
Mus musculus
Abeta(25–35) injected mouse
article
Reference: Yamada K et al.(2010) Effect of a centrally active angiotensin-converting enzyme inhibitor, perindopril, on cognitive performance in a mouse model of Alzheimers disease. Brain Res. 1352: 176-186 [PMID: 20627092]

Interaction Information:

Comment Perindopril, a centrally active ACE (angiotensin converting enzyme) inhibitor, inhibited the mouse brain ACE activities (imidapril and enalapril showed much less potent effects).
Formal Description
Interaction-ID: 17034

drug/chemical compound

Perindopril

decreases_activity of

gene/protein

ACE

in brain
Drugbank entries Show/Hide entries for Perindopril or ACE
Comment Enalapril is a non-centrally active ACE inhibitor.
Formal Description
Interaction-ID: 17039

drug/chemical compound

Enalapril

decreases_activity of

gene/protein

ACE

Drugbank entries Show/Hide entries for Enalapril or ACE
Comment Imidapril is a non-centrally active ACE inhibitor.
Formal Description
Interaction-ID: 17040

drug/chemical compound

Imidapril

decreases_activity of

gene/protein

ACE

Drugbank entries Show/Hide entries for ACE