General Information:

Id: 2,077 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Homo sapiens
article
Reference: Skidgel RA and Erdos EG(1985) Novel activity of human angiotensin I converting enzyme: release of the NH2- and COOH-terminal tripeptides from the luteinizing hormone-releasing hormone. Proc. Natl. Acad. Sci. U.S.A. 82: 1025-1029 [PMID: 2983326]

Interaction Information:

Comment LH-RH, which also contains a blocked COOH-terminal amino acid, was cleaved by human ACE at the bond between Leu-7 and Arg-8 to release the COOH-terminal tripeptide, Arg-Pro-Gly-NH2, similar to the results found with substance P.
Formal Description
Interaction-ID: 16743

gene/protein

ACE

decreases_quantity of

gene/protein

Gonadoliberin-1

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