General Information:

Id: 2,071 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Nephropathy, diabetic
Mus musculus
male
diabetic db/db mouse
article
Reference: Shibuya K et al.(2005) N-acetyl-seryl-aspartyl-lysyl-proline prevents renal insufficiency and mesangial matrix expansion in diabetic db/db mice. Diabetes 54: 838-845 [PMID: 15734863]

Interaction Information:

Comment The renal expression of TGF-beta1 was increased in db/db mice compared with db/m mice, the treatment with Ac-SDKP did not change the expression of TGF-beta1 in db/db mice.
Formal Description
Interaction-ID: 16709

organism model

db/db mouse

increases_expression of

gene/protein

TGFB1

in kidney
Drugbank entries Show/Hide entries for TGFB1