General Information:

Id: 2,042 (click here to show other Interactions for entry)
Diseases: Alzheimer disease - [OMIM]
Mus musculus
APP/PS1 transgenic mouse
brain
article
Reference: Li W et al.(2011) Regulation of matrix metalloproteinase 2 by oligomeric amyloid beta protein. Brain Res. 1387: 141-148 [PMID: 21376707]

Interaction Information:

Comment Elevated mRNA levels of MMP stimulating cytokines such as IL-1beta and TGFbeta were found in the brains of APP/PS1 mice.
Formal Description
Interaction-ID: 118572

gene/protein

MMP2

increases_activity of

gene/protein

TGFB1

in the brains of APP/PS1 mice; concerning elevated mRNA levels of MMP
Drugbank entries Show/Hide entries for MMP2 or TGFB1