General Information:

Id: 2,002 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Mus musculus
BTO:0004578 vascular smooth muscle cell
article
Reference: Zhang F et al.(2010) Different effects of angiotensin II and angiotensin-(1-7) on vascular smooth muscle cell proliferation and migration. PLoS ONE 5 [PMID: 20808802]

Interaction Information:

Comment The AT1 receptor antagonist losartan blocked Ang II-induced SMC proliferation, whilst the MAS receptor antagonist A-779 abrogated the anti-proliferative effect of Ang-(1-7) on Ang II-induced SMC proliferation.
Formal Description
Interaction-ID: 15890

drug/chemical compound

A-779

decreases_activity of

gene/protein

Angiotensin (1-7)