General Information:

Id: 1,976 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Mus musculus
leptin receptor-deficient db/db mouse and control (db/m) mouse infected with an adenovirus expressing human ACE2 (Ad-hACE2-eGFP) or the control virus (Ad-eGFP) via injection into the pancreas
Reference: Bindom SM et al.(2010) Angiotensin I-converting enzyme type 2 (ACE2) gene therapy improves glycemic control in diabetic mice. Diabetes 59: 2540-2548 [PMID: 20660625]

Interaction Information:

Comment ACE2 is a target for the prevention of beta-cell dysfunction and apoptosis occurring in type 2 diabetes.
Formal Description
Interaction-ID: 15486



affects_activity of

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