General Information:

Id: 1,970 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Homo sapiens
article
Reference: Kohlstedt K et al.(2011) Adipocyte-derived lipids increase angiotensin-converting enzyme (ACE) expression and modulate macrophage phenotype Basic Res. Cardiol. 106: 205-215 [PMID: 21116821]

Interaction Information:

Comment Human macrophage ACE expression was also upregulated by IL-4 and IL-13, which promote the alternative activation of macrophages (M2 polarization) and decreased by LPS and IFN-gamma (M1 polarization).
Formal Description
Interaction-ID: 15448

tissue/cell line

M1 macrophage

decreases_expression of

gene/protein

ACE

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