General Information:

Id: 196 (click here to show other Interactions for entry)
Diseases: Amyotrophic lateral sclerosis
Mus musculus
SOD1 wt or SOD1G93A transgenic mouse, transfected with human wt SOD1 or human SOD1G93A
BTO:0001279 spinal cord; BTO:0000312 motoneuron
Reference: Kieran D et al.(2007) Deletion of the BH3-only protein puma protects motoneurons from ER stress-induced apoptosis and delays motoneuron loss in ALS mice. Proc. Natl. Acad. Sci. U.S.A. 104 [PMID: 18077368]

Interaction Information:

Comment SOD1(G93A) mice showed an increase in ubiquitin in motoneurons during the early stage of disease progression.
Formal Description
Interaction-ID: 789

gene/protein mutant


increases_quantity of