General Information:

Id: 1,893 (click here to show other Interactions for entry)
Diseases: Alzheimer disease - [OMIM]
Reference: Vance JE and Hayashi H(2010) Formation and function of apolipoprotein E-containing lipoproteins in the nervous system Biochim. Biophys. Acta 1801: 806-818 [PMID: 20170744]

Interaction Information:

Comment Memory and learning were impaired in apo E4 knock-in mice compared to apo E3 knock-in mice.
Formal Description
Interaction-ID: 14521

gene/protein mutant

APOE (isoform E4)

decreases_activity of

compared to apo E3 knock-in mice