General Information:

Id: 1,559 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Fatty liver disease, nonalcoholic
Insulin resistance
Obesity - [OMIM]
Mus musculus
transgenic ob/ob mouse overexpressing adiponectin
article
Reference: Kim JY et al.(2007) Obesity-associated improvements in metabolic profile through expansion of adipose tissue J. Clin. Invest. 117: 2621-2637 [PMID: 17717599]

Interaction Information:

Comment The transgenic adiponectin-overexpressing ob/ob mice were morbidly obese, with significantly higher levels of adipose tissue than their ob/ob littermates, leading to an interesting dichotomy of increased fat mass associated with improvement in insulin sensitivity.
Formal Description
Interaction-ID: 11170

gene/protein

ADIPOQ

affects_activity of

disease

Obesity