General Information:

Id: 1,558 (click here to show other Interactions for entry)
Diseases: Alzheimer disease - [OMIM]
Mus musculus
senescence-accelerated mouse prone 8 (SAMP8) mouse model
article
Reference: Liu W et al.(2012) MicroRNA-16 targets amyloid precursor protein to potentially modulate Alzheimers-associated pathogenesis in SAMP8 mice Neurobiol. Aging 33: 522-534 [PMID: 20619502]

Interaction Information:

Comment Overexpression of miR-16, both in vitro and in vivo, led to reduced APP protein expression.
Formal Description
Interaction-ID: 11174

ncRNA/miRNA

mir-16

decreases_expression of

gene/protein

APP

if mir-16 is overexpressed
Drugbank entries Show/Hide entries for APP