General Information:

Id: 1,519 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Fatty liver disease, nonalcoholic
Insulin resistance
Obesity - [OMIM]
Mus musculus
male
ob/ob mouse
article
Reference: Gonzalez-Periz A et al.(2009) Obesity-induced insulin resistance and hepatic steatosis are alleviated by omega-3 fatty acids: a role for resolvins and protectins FASEB J. 23: 1946-1957 [PMID: 19211925]

Interaction Information:

Comment Representative members of the omega-3-PUFA-derived lipid mediators, namely resolvin E1 and protectin D1, mimicked the insulin-sensitizing and antisteatotic effects of omega-3-PUFAs and induced adiponectin expression to a similar extent that of rosiglitazone, a member of the thiazolidinedione family of antidiabetic drugs.
Formal Description
Interaction-ID: 10818

drug/chemical compound

Protectin D1

increases_expression of

gene/protein

ADIPOQ