General Information:

Id: 1,422 (click here to show other Interactions for entry)
Diseases: Alzheimer disease - [OMIM]
Homo sapiens
Reference: Rogers JT et al.(2008) Iron and the translation of the amyloid precursor protein (APP) and ferritin mRNAs: riboregulation against neural oxidative damage in Alzheimers disease Biochem. Soc. Trans. 36: 1282-1287 [PMID: 19021541]

Interaction Information:

Comment APP is increased after IL (interleukin)-1-mediated stress responses by translational up-regulation of APP mRNA translation at the same time by as induction of alpha-secretase activity to generate the 90 kDa APP(s) (alpha-secretase cleavage in the APP Abeta domain).
Formal Description
Interaction-ID: 9967

increases_expression of



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