General Information:

Id: 1,422 (click here to show other Interactions for entry)
Diseases: Alzheimer disease - [OMIM]
Homo sapiens
review
Reference: Rogers JT et al.(2008) Iron and the translation of the amyloid precursor protein (APP) and ferritin mRNAs: riboregulation against neural oxidative damage in Alzheimers disease Biochem. Soc. Trans. 36: 1282-1287 [PMID: 19021541]

Interaction Information:

Comment APP was regulated at the translational level by active IL (interleukin)-1 (IL-1-responsive acute box) and IRE (iron-responsive element) RNA stem-loops in the 5' untranslated region of APP mRNA.
Formal Description
Interaction-ID: 9878

gene/protein

IL1B (active form)

affects_expression of

gene/protein

APP

at translational level
Drugbank entries Show/Hide entries for APP