General Information:

Id: 1,418 (click here to show other Interactions for entry)
Diseases: Alzheimer disease - [OMIM]
Homo sapiens
BTO:0000007 HEK-293 cell
Reference: Duce JA et al.(2010) Iron-export ferroxidase activity of beta-amyloid precursor protein is inhibited by zinc in Alzheimers disease Cell 142: 857-867 [PMID: 20817278]

Interaction Information:

Comment The AD beta-amyloid protein precursor (APP) possesses ferroxidase activity mediated by a conserved H-ferritin-like active site, which is inhibited specifically by Zn2+.
Formal Description
Interaction-ID: 9795

decreases_activity of



zinc ion (2+) binding
Drugbank entries Show/Hide entries for APP