General Information:

Id: 12,020 (click here to show other Interactions for entry)
Diseases: Cardiovascular disease
Diabetes mellitus, type II - [OMIM]
Insulin resistance
Mammalia
review
Reference: Nehme A et al.An Update on the Tissue Renin Angiotensin System and Its Role in Physiology and Pathology [PMID: 30934934]

Interaction Information:

Comment Besides Ang-II production, ACE can degrade a number of vasodilating peptides including Ang-(1–7), bradykinin, and kallikrein, thus playing a central role as a vasopressor enzyme.
Formal Description
Interaction-ID: 117800

gene/protein

ACE

decreases_quantity of

gene/protein

Angiotensin (1-7)

Drugbank entries Show/Hide entries for ACE
Comment Besides Ang-II production, ACE can degrade a number of vasodilating peptides including Ang-(1–7), bradykinin, and kallikrein, thus playing a central role as a vasopressor enzyme.
Formal Description
Interaction-ID: 117804

gene/protein

Angiotensin (1-7)

increases_activity of

process

vasodilation