General Information:

Id: 11,842 (click here to show other Interactions for entry)
Diseases: Endocrine
Mus musculus
male
kidney
article
Reference: Grobe N et al.(2013) Identification of prolyl carboxypeptidase as an alternative enzyme for processing of renal angiotensin II using mass spectrometry Am. J. Physiol. 304: C945-C953 [PMID: 23392115]

Interaction Information:

Comment ACE2 metabolizes ANG II to Ang 1-7 in the kidney at neutral and basic pH, while prolylcarboxypeptidase catalyzes the same reaction at acidic pH.
Formal Description
Interaction-ID: 116927

gene/protein

PRCP

increases_quantity of

gene/protein

Angiotensin (1-7)

in kidney ; at acidic pH
Comment ACE2 metabolizes ANG II to Ang 1-7 in the kidney at neutral and basic pH, while prolylcarboxypeptidase catalyzes the same reaction at acidic pH.
Formal Description
Interaction-ID: 116928

gene/protein

ACE2

increases_quantity of

gene/protein

Angiotensin (1-7)

in kidney ; at neutral to basic pH
Drugbank entries Show/Hide entries for ACE2