General Information:

Id: 11,841 (click here to show other Interactions for entry)
Diseases: COVID-19
SARS-CoV infection
Mammalia
review
Reference: Gheblawi M et al.Angiotensin Converting Enzyme 2: SARS-CoV-2 Receptor and Regulator of the Renin-Angiotensin System [PMID: 32264791]

Interaction Information:

Comment ACE2-mediated cardiovascular protection is lost following endocytosis of the enzyme along with severe acute respiratory syndrome-coronavirus (SARS-CoV-2) viral particles.
Formal Description
Interaction-ID: 116922

process

endocytosis

decreases_activity of

gene/protein

ACE2

concerning ACE2-mediated cardiovascular protection
Drugbank entries Show/Hide entries for ACE2