General Information:

Id: 11,841 (click here to show other Interactions for entry)
Diseases: COVID-19
SARS-CoV infection
Mammalia
review
Reference: Gheblawi M et al.Angiotensin Converting Enzyme 2: SARS-CoV-2 Receptor and Regulator of the Renin-Angiotensin System [PMID: 32264791]

Interaction Information:

Comment ACE2 offers protection in acute lung injury, suggesting that, although it facilitates viral entry at the epithelial surface, the ACE2/Ang 1–7 axis can be carefully manipulated to mitigate SARS-induced tissue injuries, which represents a potential target for therapeutic intervention.
Formal Description
Interaction-ID: 116905

gene/protein

ACE2

increases_activity of

at the epithelial surface
Drugbank entries Show/Hide entries for ACE2