General Information:

Id: 11,841 (click here to show other Interactions for entry)
Diseases: COVID-19
SARS-CoV infection
Mammalia
review
Reference: Gheblawi M et al.Angiotensin Converting Enzyme 2: SARS-CoV-2 Receptor and Regulator of the Renin-Angiotensin System [PMID: 32264791]

Interaction Information:

Comment The loss of ACE2 function following binding by SARS-CoV-2 is driven by endocytosis and activation of proteolytic cleavage and processing.
Formal Description
Interaction-ID: 116903

disease

SARS-CoV-2 infection

decreases_activity of

gene/protein

ACE2

driven by endocytosis and activation of proteolytic cleavage and processing
Drugbank entries Show/Hide entries for ACE2