General Information:

Id: 11,830 (click here to show other Interactions for entry)
Diseases: SARS-CoV infection
Mus musculus
Reference: Kuba K et al.(2005) A crucial role of angiotensin converting enzyme 2 (ACE2) in SARS coronavirus-induced lung injury Nat. Med. 11: 875-879 [PMID: 16007097]

Interaction Information:

Comment SARS-CoV Spike protein binding to ACE2 in cell lines or SARS-CoV infections in vivo results in reduced ACE2 protein expression.
Formal Description
Interaction-ID: 116881


SARS-CoV S protein

decreases_expression of



Drugbank entries Show/Hide entries for ACE2