General Information:

Id: 11,823 (click here to show other Interactions for entry)
Diseases: Metabolic
Homo sapiens
Reference: Vickers C et al.(2002) Hydrolysis of biological peptides by human angiotensin-converting enzyme-related carboxypeptidase J Biol Chem 277 [PMID: 11815627]

Interaction Information:

Comment Purified human ACE2 hydrolyzes Ang II with high catalytic efficiency to produce angiotensin (1-7). The catalytic efficiency of ACE2 is 400 times higher on angiotensin II than on angiotensin I. The other peptides, angiotensin 1-9, angiotensin 1-7, and angiotensin 1-5, are poorly hydrolyzed or not hydrolyzed at all by ACE2.
Formal Description
Interaction-ID: 116804



decreases_quantity of


Angiotensin II

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