General Information:

Id: 11,822 (click here to show other Interactions for entry)
Diseases: COVID-19
Mammalia
review
Reference: Verdecchia P et al.The pivotal link between ACE2 deficiency and SARS-CoV-2 infection [PMID: 32336612]

Interaction Information:

Comment The ACE2 receptor catalyzes the removal of one single amino acid from the octapeptide angiotensin II to generate angiotensin1-7. In addition, ACE2 receptor also converts angiotensin I into angiotensin1-9, which in turn is converted to angiotensin1-7 by ACE and neprilisin. The catalytic efficiency of ACE2 is 400 times higher on angiotensin II than on angiotensin I.
Formal Description
Interaction-ID: 116793

gene/protein

ACE2

increases_quantity of

gene/protein

Angiotensin (1-9)

Drugbank entries Show/Hide entries for ACE2