General Information:

Id: 11,822 (click here to show other Interactions for entry)
Diseases: COVID-19
Reference: Verdecchia P et al.The pivotal link between ACE2 deficiency and SARS-CoV-2 infection [PMID: 32336612]

Interaction Information:

Comment The ACE2 receptor catalyzes the removal of one single amino acid from the octapeptide angiotensin II to generate angiotensin1-7. In addition, ACE2 receptor also converts angiotensin I into angiotensin1-9, which in turn is converted to angiotensin1-7 by ACE and neprilisin. The catalytic efficiency of ACE2 is 400 times higher on angiotensin II than on angiotensin I.
Formal Description
Interaction-ID: 116790



increases_quantity of


Angiotensin (1-7)

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