General Information:

Id: 11,821 (click here to show other Interactions for entry)
Diseases: COVID-19
Mammalia
review
Reference: Kai H and Kai MInteractions of coronaviruses with ACE2, angiotensin II, and RAS inhibitors-lessons from available evidence and insights into COVID-19 [PMID: 32341442]

Interaction Information:

Comment ACE2 degrades angiotensin II to generate angiotensin 1-7, which activates the mas oncogene receptor that negatively regulates a variety of angiotensin II actions mediated by angiotensin II type 1 receptor (AT1R).
Formal Description
Interaction-ID: 116757

gene/protein

ACE2

decreases_quantity of

gene/protein

Angiotensin II

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