General Information:

Id: 11,776 (click here to show other Interactions for entry)
Diseases: Cardiovascular disease
Diabetes mellitus, type II - [OMIM]
Insulin resistance
Mammalia
review
Reference: Bader M(2013) ACE2, angiotensin-(1-7), and Mas: the other side of the coin Pflugers Arch. 465: 79-85 [PMID: 23463883]

Interaction Information:

Comment Angiotensin-(1–7) [Ang-(1–7)] was discovered 1988 as a product of angiotensin I (Ang I) degradation by enzymes from the brainstem. Angiotensin-converting enzyme (ACE), which classically generates Ang II from Ang I, was shown to degrade Ang-(1–7) into inactive peptides, in particular Ang-(1–5).
Formal Description
Interaction-ID: 116574

gene/protein

ACE

decreases_quantity of

gene/protein

Angiotensin (1-7)

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