General Information:

Id: 11,751 (click here to show other Interactions for entry)
Diseases: Endocrine
Homo sapiens
CHO cells transfected with human ACE, ACE2, MME
Reference: Rice GI et al.(2004) Evaluation of angiotensin-converting enzyme (ACE), its homologue ACE2 and neprilysin in angiotensin peptide metabolism Biochem. J. 383: 45-51 [PMID: 15283675]

Interaction Information:

Comment Ang (1–7) can be generated by the action of ACE2 on Ang II or by the metabolism of Ang (1–9) by ACE and NEP (MME).
Formal Description
Interaction-ID: 116895


Angiotensin (1-9)

increases_quantity of


Angiotensin (1-7)

via catalytic action of MME (NEP)