General Information:

Id: 11,748 (click here to show other Interactions for entry)
Diseases: COVID-19
Homo sapiens
review
Reference: Sriram K and Insel PA(2020) A hypothesis for pathobiology and treatment of COVID-19: The centrality of ACE1/ACE2 imbalance Br J Pharmacol 177: 4825-4844 [PMID: 32333398]

Interaction Information:

Comment Renin cleaves AGT to form Angiotensin 1 (ANG 1), which in turn generates ANG II or ANG 1-9, primarily from the actions of ACE1 and ACE2, respectively.
Formal Description
Interaction-ID: 116366

gene/protein

ACE2

decreases_quantity of

gene/protein

Angiotensin I

Drugbank entries Show/Hide entries for ACE2