General Information:

Id: 11,717 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Mammalia
review
Reference: Graus-Nunes F and Souza-Mello V(2019) The renin-angiotensin system as a target to solve the riddle of endocrine pancreas homeostasis Biomed. Pharmacother. 109: 639-645 [PMID: 30404071]

Interaction Information:

Comment Mitochondrial metabolism plays an important role in the release of insulin and glucose homeostasis. Evidence shows that overexpression of ACE2 can regulate mitochondrial function in pancreatic beta cells and restore GSIS.
Formal Description
Interaction-ID: 116408

gene/protein

ACE2

increases_activity of

cellular component

mitochondrion

in pancreatic beta cells
Drugbank entries Show/Hide entries for ACE2