General Information:

Id: 11,717 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Mammalia
review
Reference: Graus-Nunes F and Souza-Mello V(2019) The renin-angiotensin system as a target to solve the riddle of endocrine pancreas homeostasis Biomed. Pharmacother. 109: 639-645 [PMID: 30404071]

Interaction Information:

Comment Obese animals usually showincreased expression of the systemic renin-angiotensin system (RAS)components and show high expression of local RAS elements such asangiotensin-converting enzyme (ACE) and Angiotensin II type I re-ceptor (AT1R) in the pancrea.
Formal Description
Interaction-ID: 116173

disease

Obesity

increases_expression of

gene/protein

ACE

in pancreas
Drugbank entries Show/Hide entries for ACE