General Information:

Id: 11,684 (click here to show other Interactions for entry)
Diseases: COVID-19
Cardiovascular disease
Rattus norvegicus
article
Reference: [PMID: 26171856]

Interaction Information:

Comment Ovariectomy leads to withdrawal of estrogen. It increases cardiac hypertrophy and ACE2 activity, but did not change ACE activity. Gonadectomy, withdrawal of testosterone, has the opposite effect.
Formal Description
Interaction-ID: 116065

drug/chemical compound

Estradiol

decreases_activity of

gene/protein

ACE2

in cardiac tissue
Drugbank entries Show/Hide entries for Estradiol or ACE2