General Information:

Id: 11,680 (click here to show other Interactions for entry)
Diseases: Metabolic
Muscular
Mus musculus
ACE2 KO mouse
undifferentiated mouse C2C12 myoblast cells
article/cited
Reference: Cao X et al.(2019) Angiotensin-converting enzyme 2 regulates endoplasmic reticulum stress and mitochondrial function to preserve skeletal muscle lipid metabolism Lipids Health Dis 18: 207 [PMID: 31775868]

Interaction Information:

Comment The protein levels of GRP78, eIF2alpha, ATF4, and CHOP were all significantly up-regulated in the skeletal muscle of the ACE2 KO mice.
Formal Description
Interaction-ID: 120293

gene/protein

ACE2

decreases_quantity of

gene/protein

HSPA5

in the skeletal muscle of ACE2 KO mice; GRP78 protein was up-regulated
Drugbank entries Show/Hide entries for ACE2 or HSPA5