General Information:

Id: 1,111 (click here to show other Interactions for entry)
Diseases: Alzheimer disease - [OMIM]
Mammalia
article/cited
Reference: Wyss-Coray T et al.(2001) TGF-beta1 promotes microglial amyloid-beta clearance and reduces plaque burden in transgenic mice Nat. Med. 7: 612-618 [PMID: 11329064]

Interaction Information:

Comment Cerebral TGF-beta1 levels are higher in AD cases than in nondemented controls, and TGF-beta1 immunoreactivity is increased in plaques and perivascular astrocytes.
Formal Description
Interaction-ID: 7198

increases_quantity of

gene/protein

TGFB1

Cerebral TGF-beta1 levels are higher in AD cases than in nondemented controls.
Drugbank entries Show/Hide entries for TGFB1