|
1,955
|
| 25101 |
ST-HSC (CD34(hi)CD135+Rho(hi)KSL)
|
|
increases_activity of
|
repopulation <12 weeks
|
|
in vivo
|
|
20074534
|
|
1,964
|
| 15358 |
MPP (CD150-Thy1(lo)KSL)
|
|
decreases_activity of
|
repopulation <12 weeks
|
|
in vivo
|
|
15989959
|
|
2,084
|
| 16853 |
HSC (Thy1(lo)CD135+KSL)
|
|
increases_activity of
|
repopulation <12 weeks
|
|
in vivo
|
|
16151515
|
|
2,656
|
| 25068 |
Mpl
|
|
increases_activity of
|
repopulation <12 weeks
|
compared to WT or Mpl-/-Lnk-/- double knockouts
|
in vivo
|
| 25071 |
Sh2b3
|
|
decreases_activity of
|
repopulation <12 weeks
|
compared to WT or Mpl-/-Lnk-/- double knockouts; probably through downregulating JAK2 activation
|
in vivo
|
|
18618018
|
|
2,917
|
| 31378 |
Hyaluronate
|
|
increases_activity of
|
repopulation <12 weeks
|
of HSC (Lin-Sca1+HA+)
|
in vivo
|
|
12393456
|
|
2,986
|
| 27205 |
HSC (CD34+SP,KSL)
|
|
increases_activity of
|
repopulation <12 weeks
|
|
in vivo
|
|
14738767
|
|
3,023
|
| 27710 |
HSC (SP,KSL)-aged
|
|
increases_activity of
|
repopulation <12 weeks
|
HSCs isolated from 21 month-old mice.
|
|
|
17676974
|
|
3,059
|
| 28067 |
HSC (Thy1(lo)Sca1+Lin-)
|
|
increases_activity of
|
repopulation <12 weeks
|
|
in vivo
|
|
2898810
|
|
3,106
|
| 28505 |
Bmi1
|
|
increases_activity of
|
repopulation <12 weeks
|
of HSC (Thy1(lo)KSL)
|
in vivo
|
|
12714971
|
|
3,132
|
| 39080 |
Myc
|
|
decreases_activity of
|
repopulation <12 weeks
|
|
in vivo
|
|
15545632
|
|
3,147
|
| 28965 |
Kitl
|
|
increases_activity of
|
repopulation <12 weeks
|
of BM c-Kit+ cells
|
in vivo
|
|
7544641
|
|
3,160
|
| 29080 |
Wnt3a
|
|
increases_activity of
|
repopulation <12 weeks
|
|
in vivo
|
| 29083 |
canonical Wnt signaling pathway
|
|
increases_activity of
|
repopulation <12 weeks
|
|
in vivo
|
|
18951693
|
|
3,188
|
| 29268 |
canonical Wnt signaling pathway
|
|
increases_activity of
|
repopulation <12 weeks
|
|
in vivo
|
|
12717450
|
|
3,189
|
| 29345 |
Hoxb4
|
|
increases_activity of
|
repopulation <12 weeks
|
|
in vivo
|
|
7622039
|
|
3,207
|
| 29571 |
Skp2
|
|
increases_activity of
|
repopulation <12 weeks
|
LT engraftment for 16 weeks was not influenced
|
in vivo
|
|
21502543
|
|
3,322
|
| 30529 |
Cxcr4
|
|
increases_activity of
|
repopulation <12 weeks
|
|
in vivo
|
|
18378795
|
|
3,433
|
| 31951 |
Hes1
|
|
increases_activity of
|
repopulation <12 weeks
|
|
in vivo
|
|
12406868
|
|
3,482
|
| 32373 |
Cdkn2a
|
|
decreases_activity of
|
repopulation <12 weeks
|
in old mice. There was no difference in repopulation activity of young p16Ink4a-/- mice.
|
in vivo
|
|
16957735
|
|
3,620
|
| 34252 |
smoothened signaling pathway
|
|
decreases_activity of
|
repopulation <12 weeks
|
|
in vivo
|
|
16968775
|
|
3,625
|
| 34283 |
HSC (WGA+15-1.1-Rho-)
|
|
increases_activity of
|
repopulation <12 weeks
|
compared to Rho++ or Rho+ cells
|
in vivo
|
| 34287 |
HSC (WGA+15-1.1-Rho++)
|
|
decreases_activity of
|
repopulation <12 weeks
|
compared to Rho- cells
|
in vivo
|
| 34290 |
HSC (WGA+15-1.1-Rho-/Rho(VP)-)
|
|
increases_activity of
|
repopulation <12 weeks
|
compared to Rho-/Rho(VP)+
|
in vivo
|
| 34291 |
HSC (WGA+15-1.1-Rho-/Rho(VP)+)
|
|
increases_activity of
|
repopulation <12 weeks
|
|
in vivo
|
|
7568040
|
|
3,628
|
| 34334 |
HSC (Thy1(lo)Rho(lo)Sca1+Lin-
|
|
increases_activity of
|
repopulation <12 weeks
|
|
in vivo
|
|
7849289
|
|
3,629
|
| 34351 |
HSC (SP, Lin-)
|
|
increases_activity of
|
repopulation <12 weeks
|
|
in vivo
|
|
12438646
|
|
3,814
|
| 38171 |
Cdkn2c
|
|
decreases_activity of
|
repopulation <12 weeks
|
|
in vivo
|
|
15122268
|
|
3,817
|
| 38237 |
Mapkapk2
|
|
increases_activity of
|
repopulation <12 weeks
|
of HSC (KSL)
|
in vivo
|
|
19369945
|
|
3,824
|
| 38261 |
Gfi1
|
|
increases_activity of
|
repopulation <12 weeks
|
|
in vivo
|
|
15457180
|
|
3,826
|
| 38283 |
Fancg
|
|
increases_activity of
|
repopulation <12 weeks
|
|
in vivo
|
|
21968513
|
|
3,835
|
| 38511 |
Pim kinase 1,2,3
|
|
increases_activity of
|
repopulation <12 weeks
|
in a Pim1, 2, 3 triple knockout mouse
|
in vivo
|
|
23360755
|
|
3,873
|
| 39033 |
Wnt3a
|
NOT |
affects_activity of
|
repopulation <12 weeks
|
of CD127-KSL cells
|
in vivo
|
| 39035 |
Wnt5a
|
|
increases_activity of
|
repopulation <12 weeks
|
of CD127-KSL cells
|
in vivo
|
|
17881570
|
|
3,880
|
| 39098 |
Snai2
|
|
decreases_activity of
|
repopulation <12 weeks
|
|
in vivo
|
|
20032500
|
|
3,883
|
| 39164 |
Mapk3
|
|
increases_activity of
|
repopulation <12 weeks
|
only if Erk2 has been deleted as well
|
in vivo
|
| 39166 |
Mapk1
|
|
increases_activity of
|
repopulation <12 weeks
|
only if Erk1 has been deleted as well
|
in vivo
|
|
23444405
|
HSC