7. Selenoproteins and their function in the brain

The essential trace element selenium has a strong influence on human health. It exerts its function mainly by selenoproteins having selenocysteine in their active center. The graph illustrates reactions of selenoproteins known to play a role in the progression of neurodegenerative diseases.

List all interactions Display Graph

Statistics

Interactions	88	Proteins/Genes	26	Chemical compounds/drugs	8
Biological Process(GO)	12	Phenotype	7

Proteins/Genes

SELENOK	8
SELENOP	8
GPX4	7
SELENOM	6
SELENOI	6
SELENOS	5
DERL1	5
SCLY	3
MSRB1	3
SELENOT	3
more...

Biological Process(GO)

selenocysteine incorporation	12
protein palmitoylation	3
lipid peroxidation	3
CDP-choline pathway	3
ferroptosis	2
ERAD pathway	2
selenide homeostasis	2
phospholipid biosynthetic process	2
myelination	1
calcium ion homeostasis	1
more...

Chemical compounds/drugs

Selenium	5
Phosphatidylethanolamine	4
L-Selenocysteine	3
Dopamine quinone	2
Dopamine	2
Polyunsaturated fatty acid-acyl CoA, long-chain	2
Alanine	1
Selenide	1