CIDeRplusCOVID-19: ACE2 substrates
ACE2 is a peptidase of the renin-angiotensin system. ACE2 cleaves Angiotensin II to Angiotensin (1-7), Angiotensin I to Angiotensin (1-9), and Angiotensin A to Alamandine. It also acts on other peptides: apelin, dynorphin, des-Arg9-bradykinin, neurotensin, ghrelin.
List all interactions
Display GraphStatistics
| Interactions | 64 | Proteins/Genes | 21 | Chemical compounds/drugs | 0 |
| Biological Process(GO) | 6 | Phenotype | 3 |
Proteins/Genes
| ACE2 | 47 |
| des-Arg9-bradykinin | 9 |
| Angiotensin (1-7) | 8 |
| Apelin-13 | 7 |
| Alamandine | 7 |
| Angiotensin II | 6 |
| Apelin | 3 |
| Apelin-36 | 3 |
| Angiotensin (1-9) | 3 |
| Angiotensin I | 3 |
| more... |
Biological Process(GO)
| vasodilation | 4 |
| inflammatory response | 4 |
| kallikrein-kinin system | 1 |
| cytokine secretion | 1 |
| histone acetylation | 1 |
| cognition | 1 |