Field	Query

	Field	Term

4. Alzheimer and Stress

How do microglial cells and stress interfere with Alzheimer? Beta amyloid deposits are one characteristic feature in AD. They activate microglia cells which could become a chronic source of reactive oxygen species (ROS) and increase the NADPH oxidase activity, an essential component of microglia-mediated Abeta neurotoxicity.

List all interactions Display Graph

Statistics

Interactions	12	Proteins/Genes	0	Chemical compounds/drugs	1
Biological Process(GO)	5	Phenotype	2

Proteins/Genes

Biological Process(GO)

microglial cell activation	4
neuron death	2
response to stress	2
inflammatory response	1
Abeta-mediated neurotoxicity	1

Chemical compounds/drugs

Reactive oxygen species	4

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