|
97
|
| 318 |
SOD1-p.G93A
|
|
decreases_quantity of
|
IL6
|
in adult microglia; LPS stimulated
|
|
15378658
|
Amyotrophic lateral sclerosis
|
|
385
|
| 1582 |
SOD1-p.G93A
|
|
decreases_quantity of
|
IL6
|
in TLR2 stimulated murine microglial cell line BV-2; if SOD1(G93A) is overexpressed
|
|
19091752
|
Amyotrophic lateral sclerosis
|
|
682
|
| 3716 |
Status epilepticus
|
|
increases_expression of
|
IL6
|
in pilocarpine model
|
|
19055492
|
Status epilepticus
|
|
904
|
| 5384 |
high-fat diet
|
|
increases_expression of
|
IL6
|
in liver
|
| 5388 |
SIRT1
|
NOT |
affects_expression of
|
IL6
|
in liver; in response to high-fat diet, if SIRT1 is overexpressed
|
|
18599449
|
Diabetes mellitus, type II
Insulin resistance
Fatty liver disease, nonalcoholic
|
|
952
|
| 5859 |
Diabetes mellitus, type II
|
|
increases_quantity of
|
IL6
|
in blood vessels; Diabetes accelerates the appearance of cerebrovascular inflammation evidenced by increased levels of proinflammatory cytokines IL-6 and TNF-alpha
|
|
20385830
|
Alzheimer disease
|
|
1,086
|
| 6939 |
Lipopolysaccharide
|
|
increases_expression of
|
IL6
|
|
| 6940 |
PARK7
|
|
affects_expression of
|
IL6
|
induced by LPS
|
|
19276172
|
Parkinson disease
|
|
1,092
|
| 7326 |
TLR4
|
|
increases_expression of
|
IL6
|
|
| 45978 |
adipose tissue macrophage
|
|
increases_quantity of
|
IL6
|
in adipose tissue
|
|
18053812
|
Diabetes mellitus, type II
Obesity
Insulin resistance
|
|
1,102
|
| 7023 |
Alzheimer disease
|
|
increases_quantity of
|
IL6
|
in PBMCs from AD patients compared to PBMCs in healthy controls
|
|
20462385
|
Alzheimer disease
|
|
1,103
|
| 7038 |
F2
|
|
increases_expression of
|
IL6
|
via activation of microglia in the substantia nigra
|
| 7143 |
SP600125
|
NOT |
decreases_expression of
|
IL6
|
|
| 7145 |
SB203580
|
NOT |
decreases_expression of
|
IL6
|
|
|
20025058
|
Parkinson disease
|
|
1,105
|
| 7017 |
microglial cell activation
|
|
increases_quantity of
|
IL6
|
|
|
20025058
|
Parkinson disease
|
|
1,108
|
| 7109 |
convulsive seizures
|
|
increases_expression of
|
IL6
|
|
|
1709015
|
Epilepsy
|
|
1,121
|
| 7207 |
Parkinson disease
|
|
increases_quantity of
|
IL6
|
in blood serum
|
|
18582534
|
Parkinson disease
|
|
1,122
|
| 7212 |
Parkinson disease
|
|
increases_quantity of
|
IL6
|
in striatum but not in cerebral cortex
|
|
7700568
|
Parkinson disease
|
|
1,133
|
| 7368 |
convulsive seizures
|
|
increases_expression of
|
IL6
|
|
|
19845729
|
Epilepsy, temporal lobe
|
|
1,150
|
| 7507 |
MAP3K5
|
|
increases_quantity of
|
IL6
|
after induction with LPS
|
| 7513 |
TLR4
|
|
increases_quantity of
|
IL6
|
after induction with LPS and in the presence of ASK1
|
|
15864310
|
Parkinson disease
|
|
1,158
|
| 7596 |
MAPK8
|
|
affects_expression of
|
IL6
|
in liver
|
| 7597 |
Jnk1(+/-)Jnk2(-/-) mouse
|
|
decreases_expression of
|
IL6
|
in liver
|
|
16818881
|
Diabetes mellitus, type II
Insulin resistance
|
|
1,162
|
| 7650 |
high-fat diet
|
|
increases_expression of
|
IL6
|
|
| 7690 |
IKBKB
|
|
increases_expression of
|
IL6
|
in LIKK mice
|
| 7713 |
IL6
|
|
affects_expression of
|
SOCS1
|
in muscle; in LIKK mice
|
| 7716 |
Sodium salicylate
|
|
decreases_expression of
|
IL6
|
in liver
|
| 7725 |
NFKBIA
|
|
affects_expression of
|
IL6
|
in LISR mice
|
| 13324 |
IL6
|
|
affects_expression of
|
SOCS2
|
in muscle; in LIKK mice
|
| 13327 |
IL6
|
|
affects_expression of
|
SOCS3
|
in muscle; in LIKK mice
|
| 13331 |
IL6
|
|
affects_expression of
|
STAT3
|
in muscle; in LIKK mice
|
|
15685173
|
Diabetes mellitus, type II
Insulin resistance
|
|
1,170
|
| 7730 |
Schizophrenia
|
|
increases_expression of
|
IL6
|
|
|
20510460
|
Schizophrenia
|
|
1,177
|
| 7776 |
Schizophrenia
|
|
increases_expression of
|
IL6
|
|
|
18005941
|
Schizophrenia
|
|
1,185
|
| 19317 |
Risperidone
|
NOT |
affects_expression of
|
IL6
|
|
| 19318 |
Haloperidol
|
NOT |
affects_expression of
|
IL6
|
|
|
19139851
|
Schizophrenia
|
|
1,189
|
| 7926 |
IL6
|
|
decreases_activity of
|
insulin receptor signaling pathway
|
in skeletal muscle
|
| 7927 |
IL6
|
|
decreases_activity of
|
Phosphatidylinositol 3-kinase
|
in skeletal muscle
|
| 7928 |
IL6
|
|
increases_phosphorylation of
|
STAT3
|
in skeletal muscle; at Tyr residues of STAT3
|
| 7929 |
IL6
|
|
increases_activity of
|
Insulin resistance
|
in liver
|
|
15047622
|
Diabetes mellitus, type II
Insulin resistance
|
|
1,202
|
| 8026 |
high-fat diet
|
|
increases_expression of
|
IL6
|
in liver; in Ikbkb F/F mice
|
|
15685170
|
Diabetes mellitus, type II
Insulin resistance
|
|
1,203
|
| 8071 |
CCR2
|
NOT |
affects_expression of
|
IL6
|
in adipose tissue
|
| 8073 |
CCR2
|
NOT |
affects_quantity of
|
IL6
|
in blood
|
|
16341265
|
Diabetes mellitus, type II
Obesity
Insulin resistance
|
|
1,204
|
| 8102 |
SNCA-p.A53T
|
|
increases_expression of
|
IL6
|
in the brainstem but not in the cerebral cortex of A53T mice
|
|
20409326
|
Parkinson disease
|
|
1,207
|
| 8095 |
recruited adipose tissue macrophage
|
|
affects_expression of
|
IL6
|
|
|
17192460
|
Diabetes mellitus, type II
Insulin resistance
|
|
1,211
|
| 8125 |
SNCA
|
|
increases_quantity of
|
IL6
|
in astrocytes
|
| 8126 |
SNCA-p.A30P
|
|
increases_quantity of
|
IL6
|
in astrocytes; more efficiently than WT-alpha-synuclein
|
| 8127 |
SNCA-p.E46K
|
|
increases_quantity of
|
IL6
|
in astrocytes; more efficiently than WT-alpha-synuclein
|
| 8128 |
SNCA-p.A53T
|
|
increases_quantity of
|
IL6
|
in astrocytes; more efficiently than WT-alpha-synuclein
|
| 8148 |
MAPK cascade
|
|
increases_quantity of
|
IL6
|
after addition of SNCA
|
| 8150 |
stress-activated MAPK cascade
|
|
increases_quantity of
|
IL6
|
after addition of SNCA
|
|
17012252
|
Parkinson disease
|
|
1,215
|
| 8186 |
microglial cell activation
|
|
increases_quantity of
|
IL6
|
|
|
17537546
|
Parkinson disease
|
|
1,217
|
| 8201 |
Estradiol
|
|
increases_quantity of
|
IL6
|
in blood; after 3 months of high-fat diet
|
| 8204 |
Estradiol
|
|
increases_expression of
|
IL6
|
in liver, in visceral adipose tissue; after 1 month of high-fat feeding
|
|
19164473
|
Diabetes mellitus, type II
Insulin resistance
|
|
1,218
|
| 8192 |
SNCA
|
|
increases_expression of
|
IL6
|
via microglial cell activation
|
|
17537546
|
Parkinson disease
|
|
1,232
|
| 8372 |
C3AR1
|
|
affects_expression of
|
IL6
|
|
| 8407 |
high-fat diet
|
|
increases_quantity of
|
IL6
|
|
| 8408 |
C3AR1
|
NOT |
affects_quantity of
|
IL6
|
after high-fat diet
|
|
19581423
|
Diabetes mellitus, type II
Insulin resistance
Fatty liver disease, nonalcoholic
|
CIDeRplus