Search Results for "smoothened signaling pathway" - 395 interactions found in 110 entries.

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Entry-ID
Interactor1 (Subject) Interaction type Interactor2 (Object) additional information
PubMed-ID
Diseases
5,504
53442 smoothened signaling pathway affects_activity of PDLIM3
25473003 Medulloblastoma
5,841
55181 smoothened signaling pathway increases_activity of impaired glucose tolerance in adult pancreatic beta cells
55184 smoothened signaling pathway decreases_activity of insulin secretion involved in cellular response to glucose stimulus in adult pancreatic beta cells
55185 smoothened signaling pathway decreases_activity of reduced pancreatic beta cell function in adult pancreatic beta cells
55186 smoothened signaling pathway increases_expression of BCL2 in adult pancreatic beta cells
55187 smoothened signaling pathway decreases_expression of KCNJ11 in adult pancreatic beta cells
55188 smoothened signaling pathway decreases_expression of ABCC8 in adult pancreatic beta cells
55189 smoothened signaling pathway decreases_expression of SLC2A2 in adult pancreatic beta cells
55190 smoothened signaling pathway decreases_expression of PDX1 in adult pancreatic beta cells
55191 smoothened signaling pathway decreases_expression of MAFA in adult pancreatic beta cells
55192 smoothened signaling pathway decreases_expression of NEUROD1 in adult pancreatic beta cells
55193 smoothened signaling pathway decreases_expression of NKX6-1 in adult pancreatic beta cells
55194 smoothened signaling pathway increases_expression of SOX9 in adult pancreatic beta cells
55195 smoothened signaling pathway increases_expression of HES1 in adult pancreatic beta cells
55196 smoothened signaling pathway increases_activity of increased pancreas tumor incidence in adult pancreatic beta cells
21969560 Diabetes mellitus, type II
Insulin resistance
5,856
55371 LZTFL1 affects_activity of smoothened signaling pathway
55372 BBSome affects_activity of smoothened signaling pathway
22072986 Diabetes mellitus, type II
Insulin resistance
Bardet-Biedl syndrome 17
Ciliopathy
5,860
55398 BBSome affects_activity of smoothened signaling pathway
22228099 Diabetes mellitus, type II
Insulin resistance
5,861
55401 IFT27 affects_activity of smoothened signaling pathway
25446516 Diabetes mellitus, type II
Insulin resistance
Bardet-Biedl syndrome 19
Ciliopathy
5,868
55446 SHH increases_activity of smoothened signaling pathway in primary cilium
55449 PTCH1 decreases_activity of smoothened signaling pathway in primary cilium; in the absence of SHH
55450 CDON increases_activity of smoothened signaling pathway in primary cilium; via increased binding of SHH to PTCH1
55451 BOC increases_activity of smoothened signaling pathway in primary cilium; via increased binding of SHH to PTCH1
55452 GAS1 increases_activity of smoothened signaling pathway in primary cilium; via increased binding of SHH to PTCH1
55473 GPR161 decreases_activity of smoothened signaling pathway in primary cilium
55475 SUFU decreases_activity of smoothened signaling pathway
55477 smoothened signaling pathway increases_activity of embryo development
55478 smoothened signaling pathway affects_activity of Cancer
55480 smoothened signaling pathway increases_quantity of cholangiocyte upon liver damage
55481 smoothened signaling pathway increases_quantity of myofibroblast upon liver damage
55483 smoothened signaling pathway decreases_quantity of hepatic stellate cell upon liver damage
55486 smoothened signaling pathway increases_activity of epithelial to mesenchymal transition upon liver damage
55487 smoothened signaling pathway increases_activity of liver fibrosis upon liver damage
55489 smoothened signaling pathway increases_activity of aerobic glycolysis in hepatic stellate cells; upon liver damage
55490 smoothened signaling pathway increases_activity of reverse Warburg effect in hepatocellular carcinoma cells
55491 smoothened signaling pathway affects_activity of endocrine pancreas
55492 smoothened signaling pathway affects_activity of exocrine pancreas
55493 smoothened signaling pathway affects_activity of Pancreatic cancer
55494 smoothened signaling pathway affects_expression of INS
55495 smoothened signaling pathway affects_activity of insulin secretion
55498 smoothened signaling pathway decreases_activity of fat cell differentiation in white adipose tissue
24862854 Diabetes mellitus, type II
Insulin resistance
5,886
55637 LZTFL1 rs431825171 increases_activity of smoothened signaling pathway in dermal fibroblasts
22510444 Bardet-Biedl syndrome 17
Ciliopathy
6,977
68420 IFT27 increases_activity of smoothened signaling pathway
26023097 Diabetes mellitus, type II
Insulin resistance
Bardet-Biedl syndrome 19
Ciliopathy
6,979
68532 SDCCAG8 increases_activity of smoothened signaling pathway
27224062 Bardet-Biedl syndrome 16
Ciliopathy
6,981
68588 WDPCP affects_activity of smoothened signaling pathway
24302887 Bardet-Biedl syndrome 15
Ciliopathy
7,065
69507 TCTN2 affects_activity of smoothened signaling pathway
Nephronophthisis
Senior-Loken syndrome 3
Ciliopathy
7,068
150416 TCTN1 affects_activity of smoothened signaling pathway
150417 NPHP4 affects_activity of smoothened signaling pathway
Nephronophthisis
Bardet-Biedl syndrome
Ciliopathy
7,069
69519 B9D1 affects_activity of smoothened signaling pathway
69558 B9 complex affects_activity of smoothened signaling pathway
Bardet-Biedl syndrome
Joubert syndrome
Meckel syndrome
Ciliopathy
7,083
69600 Intraflagellar transport complex A increases_activity of smoothened signaling pathway
Nephronophthisis 13
Senior-Loken syndrome 8
Ciliopathy
7,085
69721 TRAF3IP1 affects_activity of smoothened signaling pathway
Senior-Loken syndrome 9
Ciliopathy
7,102
69880 TTC21B affects_activity of smoothened signaling pathway
69899 cilium affects_activity of smoothened signaling pathway
Nephronophthisis
Ciliopathy
7,103
69969 GLIS2 affects_activity of smoothened signaling pathway
69970 CEP290 affects_activity of smoothened signaling pathway
Nephronophthisis
Ciliopathy
7,108
70025 TTC21B decreases_activity of smoothened signaling pathway
Nephronophthisis 12
Ciliopathy
7,110
70027 TTC21B decreases_activity of smoothened signaling pathway
Diabetes mellitus, type II
Insulin resistance
Nephronophthisis 12
Ciliopathy
7,111
70065 TTC21B rs140511594 NOT affects_activity of smoothened signaling pathway
Diabetes mellitus, type II
Insulin resistance
Nephronophthisis 12
Ciliopathy
7,121
70145 GLIS2 affects_activity of smoothened signaling pathway
19118152 Nephronophthisis
Ciliopathy
7,124
70188 ZNF423 affects_activity of smoothened signaling pathway
Nephronophthisis 14
Ciliopathy
7,127
70218 CC2D2A affects_activity of smoothened signaling pathway
Joubert syndrome 9
Meckel syndrome, type 6
Ciliopathy
7,156
70401 GLIS2 decreases_activity of smoothened signaling pathway in postnatal kidney
Nephronophthisis 7
Ciliopathy
7,157
70442 smoothened signaling pathway increases_transport of GLI3 into the nucleus
70477 smoothened signaling pathway increases_expression of INS
Diabetes mellitus, type II
Diabetes mellitus, type I
Insulin resistance
Nephronophthisis 7
Ciliopathy
7,164
70527 WNT5A decreases_activity of smoothened signaling pathway in embryonic lung
Nephronophthisis 11
COACH syndrome
Meckel syndrome, type 3
Joubert syndrome 6
Ciliopathy
7,168
70562 DZIP1 affects_activity of smoothened signaling pathway
Nephronophthisis 15
Ciliopathy
7,171
70587 DCDC2 affects_activity of smoothened signaling pathway
Nephronophthisis 19
Ciliopathy
7,172
70417 smoothened signaling pathway affects_activity of stem cell population maintenance
70596 smoothened signaling pathway affects_activity of neoplasm
70597 cilium increases_activity of smoothened signaling pathway
70598 intraciliary transport increases_activity of smoothened signaling pathway
70599 smoothened signaling pathway affects_activity of positive regulation of embryonic development
70607 KIF3A increases_activity of smoothened signaling pathway
70631 DYNC2H1 affects_activity of smoothened signaling pathway
Joubert syndrome
Ciliopathy
Short-rib thoracic dysplasia 3 with or without polydactyly
Acrocallosal syndrome
7,202
70910 INPP5E affects_activity of smoothened signaling pathway
Joubert syndrome 1
Ciliopathy
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