46
|
122 |
Streptozocin
|
|
increases_activity of
|
response to oxidative stress
|
|
134 |
Arjunolic acid
|
|
decreases_activity of
|
response to oxidative stress
|
in STZ treated rats under hyperglycemic condition
|
|
19133311
|
Diabetes mellitus, type I
|
58
|
185 |
IL1B
|
|
increases_activity of
|
response to oxidative stress
|
|
|
19071154
|
Diabetes mellitus, type I
|
122
|
620 |
response to oxidative stress
|
|
decreases_activity of
|
GSK3B
|
|
|
11527574
|
Alzheimer disease
|
339
|
1333 |
Pilocarpine
|
|
increases_activity of
|
response to oxidative stress
|
in pilocarpine rat model
|
1334 |
Buspirone hydrochloride
|
|
decreases_activity of
|
response to oxidative stress
|
in pilocarpine rat model
|
13705 |
response to oxidative stress
|
|
increases_quantity of
|
NO
|
in pilocarpine rat model
|
13706 |
response to oxidative stress
|
|
increases_activity of
|
lipid oxidation
|
in pilocarpine rat model
|
|
19800952
|
Status epilepticus
|
379
|
1553 |
Lipophilic metal chelator DP-109
|
|
decreases_activity of
|
response to oxidative stress
|
in SOD1(G93A) transgenic mice
|
1554 |
Lipophilic metal chelator DP-460
|
|
decreases_activity of
|
response to oxidative stress
|
in SOD1(G93A) transgenic mice
|
|
17630988
|
Amyotrophic lateral sclerosis
|
385
|
1592 |
SOD1-p.G93A
|
|
increases_activity of
|
response to oxidative stress
|
in TLR2 or TLR4 stimulated murine microglial cell line BV-2; if SOD1(G93A) is overexpressed
|
1595 |
NCF1
|
|
affects_activity of
|
response to oxidative stress
|
in TLR2 stimulated murine microglial cell line BV-2; if SOD1(G93A) is overexpressed
|
|
19091752
|
Amyotrophic lateral sclerosis
|
421
|
1841 |
PINK1
|
|
affects_activity of
|
response to oxidative stress
|
|
|
19251702
|
Parkinson disease
|
448
|
1987 |
LRRK2-mut
|
|
increases_activity of
|
response to oxidative stress
|
|
2002 |
EIF4EBP1
|
|
affects_activity of
|
response to oxidative stress
|
|
|
18701920
|
Parkinson disease
|
457
|
2078 |
response to oxidative stress
|
|
increases_activity of
|
GSK3B
|
|
36317 |
response to oxidative stress
|
|
increases_activity of
|
intrinsic apoptotic signaling pathway in response to oxidative stress
|
|
|
19712582
|
Alzheimer disease
|
467
|
2115 |
H2O2
|
|
increases_activity of
|
response to oxidative stress
|
|
2130 |
response to oxidative stress
|
|
increases_activity of
|
neuron death
|
|
4409 |
ERK1 and ERK2 cascade
|
|
decreases_activity of
|
response to oxidative stress
|
if oxidative stress has been induced by H2O2
|
|
18675914
|
Parkinson disease
|
533
|
2671 |
response to oxidative stress
|
|
increases_quantity of
|
NEFH-mod
|
|
|
18635547
|
Alzheimer disease
Amyotrophic lateral sclerosis
|
537
|
2737 |
PINK1
|
|
affects_activity of
|
response to oxidative stress
|
|
|
19270741
|
Parkinson disease
|
591
|
3116 |
SOD1-p.H46R
|
|
increases_activity of
|
response to oxidative stress
|
in mitochondria
|
13773 |
SOD1-p.H80R
|
|
increases_activity of
|
response to oxidative stress
|
in mitochondria
|
13778 |
SOD1-p.D124V
|
|
increases_activity of
|
response to oxidative stress
|
in mitochondria
|
13783 |
SOD1-p.G85R
|
|
increases_activity of
|
response to oxidative stress
|
in mitochondria
|
13788 |
SOD1-p.A4V
|
|
increases_activity of
|
response to oxidative stress
|
in mitochondria
|
13793 |
SOD1-p.G93A
|
|
increases_activity of
|
response to oxidative stress
|
in mitochondria
|
|
16945901
|
Amyotrophic lateral sclerosis
|
646
|
3425 |
response to oxidative stress
|
|
increases_quantity of
|
SOD1 protein aggregates
|
|
3430 |
response to oxidative stress
|
|
increases_ubiquitination/sumoylation of
|
SOD1-mod
|
|
3431 |
response to oxidative stress
|
|
increases_ubiquitination/sumoylation of
|
SOD1-p.G93A
|
|
|
17394546
|
Amyotrophic lateral sclerosis
|
672
|
3729 |
Status epilepticus
|
|
affects_activity of
|
response to oxidative stress
|
in lithium-pilocarpine model
|
3730 |
response to oxidative stress
|
|
affects_activity of
|
neuron death
|
in lithium-pilocarpine model
|
|
20149694
|
Status epilepticus
|
685
|
3719 |
LRRK2
|
|
increases_activity of
|
response to oxidative stress
|
if overexpressed
|
3720 |
LRRK2-p.G2019S
|
|
increases_activity of
|
response to oxidative stress
|
cell death was increased with a higher rate than wild type
|
3734 |
PARK7
|
|
decreases_activity of
|
response to oxidative stress
|
|
|
19769964
|
Parkinson disease
|
713
|
4004 |
BCL2L1
|
|
decreases_activity of
|
response to oxidative stress
|
in primary astrocytes
|
|
19179380
|
Amyotrophic lateral sclerosis
|
737
|
10817 |
response to oxidative stress
|
|
increases_activity of
|
re-entry into mitotic cell cycle
|
if oxidative stress has been induced by 6-OHD
|
|
18665912
|
Parkinson disease
|
757
|
4291 |
response to oxidative stress
|
|
decreases_activity of
|
CKM
|
|
4292 |
response to oxidative stress
|
|
decreases_activity of
|
GAPDH
|
|
|
18706911
|
Amyotrophic lateral sclerosis
|
851
|
5063 |
response to oxidative stress
|
|
increases_phosphorylation of
|
AKT1
|
in the presence of DJ-1
|
5066 |
response to oxidative stress
|
|
increases_activity of
|
protein kinase B signaling
|
in the presence of DJ-1
|
|
20133695
|
Parkinson disease
|
904
|
13193 |
SIRT1
|
|
decreases_activity of
|
response to oxidative stress
|
if SIRT1 is overexpressed
|
|
18599449
|
Diabetes mellitus, type II
Insulin resistance
Fatty liver disease, nonalcoholic
|
908
|
5414 |
Alzheimer disease
|
|
increases_activity of
|
response to oxidative stress
|
|
5416 |
response to oxidative stress
|
|
affects_quantity of
|
Amyloid beta peptide (39-43)
|
|
5557 |
Curcumin
|
|
increases_activity of
|
response to oxidative stress
|
|
10906 |
response to oxidative stress
|
|
affects_quantity of
|
Amyloid beta peptide (42)
|
|
|
19191039
|
Alzheimer disease
|
927
|
5608 |
response to oxidative stress
|
|
increases_expression of
|
PRKN
|
|
|
17314283
|
Parkinson disease
|
942
|
5715 |
response to oxidative stress
|
|
increases_quantity of
|
alpha-synuclein inclusion body
|
|
|
20164329
|
Parkinson disease
Synucleinopathy
|
974
|
6020 |
NQO1
|
|
decreases_activity of
|
response to oxidative stress
|
|
|
17015834
|
Parkinson disease
|
977
|
6034 |
NQO1
|
|
decreases_activity of
|
response to oxidative stress
|
|
|
15312971
|
Parkinson disease
|
979
|
6512 |
NFE2L2
|
|
decreases_activity of
|
response to oxidative stress
|
by stabilizing antioxidant transcriptional master regulator Nrf2
|
|
17015834
|
Parkinson disease
|
986
|
6110 |
response to oxidative stress
|
|
increases_transport of
|
PARK7
|
into mitochondrial outer membrane
|
10456 |
response to oxidative stress
|
|
increases_quantity of
|
PARK7
|
in mitochondria
|
|
15181200
|
Parkinson disease
|
999
|
6205 |
amyloid beta deposits
|
|
affects_activity of
|
response to oxidative stress
|
|
6208 |
Ginkgo biloba
|
|
decreases_activity of
|
response to oxidative stress
|
|
6209 |
alpha-Tocopherol
|
|
decreases_activity of
|
response to oxidative stress
|
|
|
17086105
|
Alzheimer disease
|
1,004
|
6260 |
SOD1-p.G93A
|
|
increases_activity of
|
response to oxidative stress
|
|
|
12654515
|
Amyotrophic lateral sclerosis
|